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Drug Delivery

Dr. Wang’s early publications directly addressed the research and engineering of biodegradable and biocompatible materials for drug delivery. He explored the application of natural polymers to make drug loaded fibers for wound healing [1, 2, 3, 6]. The drug loaded fibers can provide sustained release to wound and accelerate the healing process. He also used synthetic polymers to make drug loaded particles for sustained release of insulin and vaccines [4, 5].

 

SEM of biodegradable and biocompatible chitosan fibers and their properties for drug controlled release [1].

SEM of biodegradable and biocompatible chitosan fibers and their properties for drug controlled release [1].


1) Wang Q, Zhang N, Hu X, Yang J, Du Y. Chitosan/starch fibers and their properties for drug controlled release. European journal of pharmaceutics and biopharmaceutics. 2007; 66(3):398-404. PMID: 17196808
2) Wang Q, Zhang N, Hu X, Yang J, Du Y. Alginate/polyethylene glycol blend fibers and their properties for drug controlled release. Journal of biomedical materials research. Part A. 2007; 82(1):122-8. PMID: 17269140
3) Wang Q, Zhang N, Hu X, Yang J, Du Y. Chitosan/polyethylene glycol blend fibers and their properties for drug controlled release. Journal of biomedical materials research. Part A. 2008; 85(4):881-7. PMID: 17907240
4) Büyüktimkin B, Wang Q, Kiptoo P, Stewart JM, Berkland C, Siahaan TJ. Vaccine-like controlled-release delivery of an immunomodulating peptide to treat experimental autoimmune encephalomyelitis. Molecular pharmaceutics. 2012; 9(4):979-85. PMID: 22375937
5) Gu Z, Aimetti AA, Wang Q, Dang TT, Zhang Y, Veiseh O, Cheng H, Langer RS, Anderson DG. Injectable nano-network for glucose-mediated insulin delivery. ACS nano. 2013; 7(5):4194-201. PMID: 23638642

6) Xin S, Li X, Wang Q, Huang R, Xu X, Lei Z, Deng H. Novel layer-by-layer structured nanofibrous mats coated by protein films for dermal regeneration. Journal of biomedical nanotechnology. 2014; 10(5):803-10. PMID: 24734533


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