Wang Lab


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Gut Organoid Paper in Marine Drugs

Dr. Zahra Davoudi’s paper, “Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery“, has been published on Marine Drugs. In this study, the impact of surface charge on the delivery of 5-ASA loaded PLGA nanoparticles into the lumen of organoids was investigated. It was concluded that the positively charged chitosan nanoparticles were more readily transported across the epithelium into the lumen than the negatively charged alginate nanoparticles. Thus, the organoid can be utilized as an appropriate model to mimic the functions of the intestinal epithelium and can be used as a model to evaluate the benefits of nanoparticle-based drug delivery. Congratulations to the team!

Graduation Ceremony 2021

It’s so happy to meet with students at the Iowa State Graduation Ceremony. Congratulations to all fellow students of the Class of 2021. Good luck with your future career!

Elected as Officers of Society For Biomaterials

Dr. Wang has been elected as a member of the Publications Committee for Society For Biomaterials. This appointment is a four-year term that begins in May 2021 and ends in April 2025. Also, Dr. Wang will work as the Secretary and Treasurer for the Tissue Engineering Special Interest Group (SIG). Congratulations!

Georgia, welcome!

CBE undergraduate students, Georgia Wimmer will join Wang Lab as a summer researcher to work on the Organoids projects. Welcome!

Presentation at NIDA Genetic Consortium

Dr. Wang will give a presentation at the NIDA Genetic Consortium Meetings, March 8th to 10th. The topic is to use “Organoids as New Platform to Study Substance Use Disorders”. The mission is to promote NIDA’s genetic and epigenetic research relevant to substance use disorders and addictive behaviors. You can join me through the

Presentation at TMSCA

Dr. Wang gave a presentation about tissue engineering and regenerative medicine using organoids at Translational Medicine and Stem Cell Association (TMSCA) at UC Berkeley. The most recent research progress on biomaterials mediated organoids and stem cell reprogramming and organoids and cell-mediated drug delivery has been discussed. Stem cell research at UC Berkeley is organized and coordinated by the Berkeley Stem Cell Center, a cornerstone of the University’s Health Sciences Initiative.

Most Cited Paper

Our drug delivery paper, “Folate Receptor-Targeted and
GSH-Responsive Carboxymethyl Chitosan Nanoparticles Containing
Covalently Entrapped 6-Mercaptopurine for Enhanced Intracellular Drug
Delivery in Leukemia
“, is among the Top 25 Most Cited Papers of Marine
, since 2018. Congratulations!

Hi, Dr. Davoudi and Dr. Qi!

Dr. Zahra Davoudi and Dr. Yijun Qi have successfully defended the thesis for Doctor of Philosophy. Congratulations!

Presentation at WBC 2020

Dr. Wang will present “Manipulate Intestinal Organoids with Niobium Carbide Nanosheets” at World Biomaterials Congress (WBC) 2020, 11-15 December 2020. We are looking forward to sharing latest progress from Wang Lab with you. Cheers~

Congratulations to Dr. Sun!

Dr. Sun’s new manuscript, “TNFα Regulates Intestinal Organoids from Mice with Both Defined and Conventional Microbiota “, has been published on International Journal of Biological Macromolecules. Thanks to all collaborators on this long-term project. Dr. Rollins, Dr. Mansell, Dr. Jergens, Dr. Phillips, and Dr. Wannemuehler. Thanks to all members in the team. Congratulations!