Yijun Qi’s new manuscript, “Transport of Artificial Virus-like Nanocarriers (AVN) through Intestinal Monolayer via Microfold Cells“, has been published on Nanoscale. It is collaboration with Tianjian Tong @ Prof. Chenxu Yu’s lab. In this study, inspired by mammalian orthoreovirus (MRV) transport into gut mucosal lymphoid tissue via Microfold cells (M cells), artificial virus-like nanocarriers (AVN), consisting of gold nanocages functionalized with the σ1 protein from mammalian reovirus (MRV), were tested as an effective oral vaccine delivery vehicle targeting M cells. AVN was shown to have a significantly higher transport compared to other experimental groups across mouse organoid monolayers containing M cells. These findings suggest that AVN has the potential to be an M cell-specific oral vaccine/drug delivery vehicle. Congratulations!
Brittney Reding’s new manuscript, “Manipulate Intestinal Organoids with Niobium Carbide Nanosheets“, has been published on Journal of Biomedical Materials Research Part A. In this study, Nb2C nanosheets were prepared by spark plasma sintering and HF etching. The results show overall potential benefits of placing low concentration Nb2C nanosheets in intestinal systems to protect and stimulate cell survivability when undergoing various treatments. Brittney is an undergradate research who has worked in Wang Lab since 2018. Congratulations!
Zahra’s new book chapter, “Skin Tissue Engineering with Nanostructured Materials“, has been published on Imaging Technologies and Transdermal Delivery in Skin Disorders. This timely book by Wiley‐VCH covers the latest understanding about today’s major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. Congratulations!
Dr. Wang has been invited to 2020 World Biomaterials Congress to present the research “Manipulate Intestinal Organoids with Niobium Carbide Nanosheets”. See you at Glasgow, Scotland in May!
In 2019, there are 6 manuscripts being published in peer-reviewed journals. Congratulations to all lab members and collaborators. We look forward a more productive 2020!
Working with Dr. Mansell (PI), Dr. Wang has been awarded the National Institutes of Health (NIH)/ National Institute of General Medical Sciences (NIGMS) Exploratory Research R21. Wang Lab and Mansell Lab will work together to co-culture engineered probiotic bacteria to accurately monitor and actively influence the development of intestinal epithelial cells in 3D culture. Congratulation!
Dr. Wang has been invited to serve as Editorial Board Member of Molecules. Molecules is a peer-reviewed is the leading international peer-reviewed journal of chemistry. Molecules is published monthly online by MDPI. The 2016 Impact Factor is 2.861 ; the 5-Year Impact Factor is 2.988. Congratulations!
Dr. Wang has been reorganized during award recipient ceremony in 2018 Association for Clinical and Translational Science (ACTS) Annual Meeting in Washington, DC on April 20th, 2018! Wang Lab was very honored and grateful to be a recipient of the precious PhRMA Foundation Research Starter Award. Congratulations!
Both Zahra’s abstract “Intestinal Organoids Containing PLGA Nanoparticles for the Treatment of Inflammatory Bowel Diseases“, and Martin’s abstract “Alternative Foaming Agents for Topical Treatment of Ulcerative Colitis” have been accepted for Oral Presentations at the Society For Biomaterials 2018 Annual Meeting and Exposition: Exploring the Nexus of Research and Application, being held April 11 – 14, 2018 in Atlanta, GA, USA. All my friends, see you in Atlanta!
New Ph.D. students, Prerana Ganguly and Chang Yong Oh will join Wang Lab as graduate researcher to work on stem cells reprogramming and cell-mediated drug deliver projects. Welcome!